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研究发现高脂肪食物可缓解低落情绪

很多健康知识都提醒人们当心高脂肪食物带来的“健康负担”。然而比利时科研人员日前发现,这类食物可通过胃影响大脑,缓解糟糕的情绪,但这一发现不能成为心情抑郁者胡吃海塞的依据。

高脂肪食物可通过胃影响大脑,缓解糟糕的情绪

高脂肪食物可通过胃影响大脑,缓解糟糕的情绪

比利时鲁汶大学的一个科研小组日前发布的研究报告说,这个小组征集了12名体重正常的志愿者,让他们看一组令人伤感的图片,听旋律忧伤的音乐,同时用功能性磁共振成像技术扫描他们的脑部。

随后,研究人员通过饲管向一半志愿者的胃部注入脂肪酸,它是甘油三酯的主要成分,其他志愿者的胃中则注入生理盐水。为避免被测试者对食物展开联想并影响心理活动,他们事先未被告知摄入的是什么。

研究结果显示,伤感的音乐和图片使志愿者的情绪全面低落,但摄入脂肪酸的志愿者比摄入盐水者的悲伤程度轻50%。这是因为当脂肪酸注入前者的胃部后,与其忧伤情绪相关的大脑部位的活动受到抑制。

研究小组的负责人卢卡斯·范奥登霍弗博士说:“看起来,食用脂肪能减少我们的悲伤程度。”科研人员还认为,上述发现对肥胖人群、饮食紊乱症和抑郁症患者的治疗可能具有重要意义。在今后的深入研究中,这个小组将力求征集更多志愿者。

美国全国糖尿病、消化道和肾脏疾病研究所的专家乔瓦尼·奇扎在评论这一研究结果时表示,如果没有感官刺激,人们就不知道注入胃里的是什么,胃在接触不同食物后一定有途径与大脑分别进行特殊交流。但健康专家也提醒说,如果某些心情长期抑郁者的若干健康指标本已不正常,那么指望吃高脂肪食品缓解忧虑的做法对其有害无益。

 

英文论文摘要:

Fatty acid–induced gut-brain signaling attenuates neural and behavioral effects of sad emotion in humans

Although a relationship between emotional state and feeding behavior is known to exist, the interactions between signaling initiated by stimuli in the gut and exteroceptively generated emotions remain incompletely understood. Here, we investigated the interaction between nutrient-induced gut-brain signaling and sad emotion induced by musical and visual cues at the behavioral and neural level in healthy nonobese subjects undergoing functional magnetic resonance imaging. Subjects received an intragastric infusion of fatty acid solution or saline during neutral or sad emotion induction and rated sensations of hunger, fullness, and mood. We found an interaction between fatty acid infusion and emotion induction both in the behavioral readouts (hunger, mood) and at the level of neural activity in multiple pre-hypothesized regions of interest. Specifically, the behavioral and neural responses to sad emotion induction were attenuated by fatty acid infusion. These findings increase our understanding of the interplay among emotions, hunger, food intake, and meal-induced sensations in health, which may have important implications for a wide range of disorders, including obesity, eating disorders, and depression.

 

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