图表盘点|那些年ACC/AHA更新过的心衰指南要点
编译整理,未经授权,请勿转载。
近年来,美国心脏病学会(ACC)和美国心脏协会(AHA)不断更新其心力衰竭治疗指南。但每部指南都不可能是完美的,所以以往的指南仍需要继续更新。
一、生物标志物
第一次指南更新是生物标志物的相关内容,这类标志物在心衰诊断中具有重要的作用。医生可能对呼吸困难的患者一无所知,但BNP可以帮你鉴别患者是心脏病变还是肺部病变。
生物标志物的应用
风险分层
二、HFrEF
然后是与射血分数降低性心衰(HFrEF)治疗相关的更新。
C期HFrEF的药物治疗
三、HFpEF
最后是与射血分数保留性心衰相关的治疗更新。这令医生们非常激动,因为这是我们首次看到了HFpEF的明确治疗推荐。
1.C期HFpEF患者的药物治疗
2.C期HFpEF合并冠心病、房颤的治疗
四、合并症处理
对于合并贫血、高血压及睡眠障碍的患者,指南更新的推荐如下。
1.贫血
2.高血压
3.睡眠障碍
参考文献
1.Yancy CW, Jessup M, Bozkurt B, et al. 2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. J Am Coll Cardiol. 2017 Apr 21.
2.Yancy CW, Jessup M, Bozkurt B, et al; American College of Cardiology Foundation; American Heart Association Task Force on Practice Guidelines. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2013;62:e147-e239.
3.McMurray JJ, Packer M, Desai AS, et al; PARADIGM-HF Investigators and Committees. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014;371:993-1004.
4.Pitt B, Pfeffer MA, Assmann SF, et al; TOPCAT Investigators. Spironolactone for heart failure with preserved ejection fraction. N Engl J Med. 2014;370:1383-1392.
5.Yusuf S, Pfeffer MA, Swedberg K, et al; CHARM Investigators and Committees. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet. 2003;362:777-781.
6.SPRINT Research Group, Wright JT Jr, Williamson JD, et al. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373:2103-2116.
7.Cowie MR, Woehrle H, Wegscheider K, et al. Adaptive servo-ventilation for central sleep apnea in systolic heart failure. N Engl J Med. 2015;373:1095-1105.
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